Investigating the link between environmental factors and heart disease risk in patients with substance use disorder.
Redox, Environmental, and Metabolomics: investigating Disease Yield (REMEDY)
This study is looking at how certain chemicals in the blood might affect heart disease risk in people with substance use disorder, and it aims to gather information that could help improve treatments for these individuals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project ID | NIH-11194080 on NIH RePORTER |
What this research studies
This research explores how certain chemicals in the blood, known as volatile organic compounds (VOCs), relate to heart disease risk in individuals with substance use disorder (SUD). By analyzing data from over 101,000 participants, the study will measure oxidative balance scores (OBS) and VOC levels to understand their connection to cardiovascular disease (CVD). The research will involve collecting plasma samples from 800 patients to identify those with SUD and assess their oxidative stress and heart disease risk. The goal is to create a centralized database that can help in understanding these relationships and potentially guide future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with substance use disorder who may also be at risk for cardiovascular disease.
Not a fit: Patients without substance use disorder or those not at risk for cardiovascular disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and targeted interventions for cardiovascular disease in patients with substance use disorder.
How similar studies have performed: Previous research has shown promising results in linking environmental factors and biomarkers to cardiovascular risks, suggesting that this approach may yield valuable insights.
Where this research is happening
Shreveport, United States
- Louisiana State Univ Hsc Shreveport — Shreveport, United States (Active)
Researchers
- Principal investigator: Bhuiyan, Mohammad Alfrad Nobel — Louisiana State Univ Hsc Shreveport
- Study coordinator: Bhuiyan, Mohammad Alfrad Nobel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.