Investigating the link between diabetic pregnancies and fetal heart defects
Official title: Clinical, Histological, and Transcriptional Associations Between the Diabetic Placenta and Fetal Congenital Heart Defects
Funded at University of Florida · NIH-10823771 · Data updated 2026-11-12
This study is looking at how diabetes in pregnant women might impact the placenta and contribute to heart problems in their babies, and it’s for expectant moms who want to understand more about the health of their little ones.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | August 16, 2024 |
| Project end | August 15, 2028 |
| Funding year | 2024 |
| Award (this year) | $43,163 |
| NIH project number | 1F30HL172988-01 |
| Project ID | NIH-10823771 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women with pregestational diabetes who are at risk of having a child with congenital heart defects.
✕Less likely to help
Patients who do not have diabetes or are not pregnant may not benefit from this research.
What this research studies
This research aims to explore how maternal diabetes affects the placenta and its potential role in causing congenital heart defects in fetuses. By examining the placental tissue and associated biological markers, the study seeks to uncover the mechanisms behind these heart defects, which are more common in pregnancies complicated by diabetes. The research will involve a combination of clinical assessments and laboratory analyses to gather comprehensive data on the relationship between diabetes and fetal heart health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for congenital heart defects in infants born to diabetic mothers.
How similar studies have gone: Previous research has indicated a correlation between maternal health conditions and fetal development, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Mahadevan, Aditya Devidas — University of Florida
- Study coordinator: Mahadevan, Aditya Devidas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.