Investigating the link between diabetic pregnancies and fetal heart defects
Clinical, Histological, and Transcriptional Associations Between the Diabetic Placenta and Fetal Congenital Heart Defects
This study is looking at how diabetes in pregnant women might impact the placenta and contribute to heart problems in their babies, and it’s for expectant moms who want to understand more about the health of their little ones.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10823771 on NIH RePORTER |
What this research studies
This research aims to explore how maternal diabetes affects the placenta and its potential role in causing congenital heart defects in fetuses. By examining the placental tissue and associated biological markers, the study seeks to uncover the mechanisms behind these heart defects, which are more common in pregnancies complicated by diabetes. The research will involve a combination of clinical assessments and laboratory analyses to gather comprehensive data on the relationship between diabetes and fetal heart health.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women with pregestational diabetes who are at risk of having a child with congenital heart defects.
Not a fit: Patients who do not have diabetes or are not pregnant may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for congenital heart defects in infants born to diabetic mothers.
How similar studies have performed: Previous research has indicated a correlation between maternal health conditions and fetal development, suggesting that this approach may yield valuable insights.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Mahadevan, Aditya Devidas — University of Florida
- Study coordinator: Mahadevan, Aditya Devidas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.