Investigating the link between depression and immune response in women with HIV

The Neuroimmunology of Depression in Women Living With HIV

['FUNDING_R01'] · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · NIH-11061532

This study is looking at how HIV affects the immune system and can lead to depression in women living with the virus, and it aims to find ways to help improve their mental health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MIAMI SCHOOL OF MEDICINE (nih funded)
Locations1 site (CORAL GABLES, UNITED STATES)
Trial IDNIH-11061532 on ClinicalTrials.gov

What this research studies

This research focuses on understanding how HIV infection affects the immune system and contributes to depression in women living with HIV. By examining the relationship between systemic inflammation and changes in brain chemistry, the study aims to uncover the mechanisms that lead to higher rates of depression in this population. The research will utilize data from established cohorts of women with and without HIV to explore these connections and identify potential therapeutic targets. Patients may undergo assessments related to their immune function and mental health as part of this investigation.

Who could benefit from this research

Good fit: Ideal candidates for this research are women aged 21 and older who are living with HIV and experiencing symptoms of depression.

Not a fit: Patients who are not women or those who do not have HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for depression in women living with HIV, enhancing their overall health and quality of life.

How similar studies have performed: Previous research has shown promising results in understanding the neuroimmunological aspects of depression, suggesting that this approach could yield valuable insights.

Where this research is happening

CORAL GABLES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, Affective Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.