Investigating the link between aging, pesticide exposure, and Parkinson's disease
BLRD Research Career Scientist Award Application
This study is looking at how getting older and being around pesticides might raise the chances of developing Parkinson's disease in older veterans, and it’s exploring whether some approved medications can help protect the brain by lowering certain harmful substances.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | South Texas Veterans Health Care System NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11105788 on NIH RePORTER |
What this research studies
This research focuses on understanding how aging and exposure to pesticides may increase the risk of developing Parkinson's disease, particularly in older veterans. It aims to explore the role of elevated biogenic aldehydes in the disease's progression and whether certain FDA-approved drugs can lower these compounds to provide neuroprotection. By conducting preclinical studies, the research seeks to establish a foundation for future clinical trials that could lead to effective treatments for Parkinson's disease in older populations.
Who could benefit from this research
Good fit: Ideal candidates for participation are older veterans, especially those with a history of pesticide exposure.
Not a fit: Patients who are younger than 65 or do not have a history of pesticide exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new neuroprotective treatments for Parkinson's disease, particularly benefiting older veterans.
How similar studies have performed: Previous research has shown promising results in understanding the links between environmental toxins and neurodegenerative diseases, suggesting that this approach may yield valuable insights.
Where this research is happening
San Antonio, United States
- South Texas Veterans Health Care System — San Antonio, United States (Active)
Researchers
- Principal investigator: Strong, Randy — South Texas Veterans Health Care System
- Study coordinator: Strong, Randy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.