Investigating the impact of stress on heart failure

Stress and Congestive Heart Failure: A mechanistic clinical trial

NIH-funded research Yale University · NIH-10892076

This study is looking at how stress impacts people with heart failure, aiming to find out what triggers stress that can make their symptoms worse, so we can help them manage their condition better and avoid hospital visits.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10892076 on NIH RePORTER

What this research studies

This research focuses on understanding how psychological stress affects patients with heart failure, which is a condition that significantly reduces quality of life and leads to frequent hospital admissions. The study aims to identify stress-related triggers that can worsen heart failure symptoms and lead to hospitalizations. By using advanced technology, such as wireless hemodynamic monitors, the research seeks to capture early signs of heart failure decompensation, allowing for timely interventions. Patients will be monitored to assess the relationship between stress and heart failure events, potentially leading to improved management strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with heart failure who experience significant psychological stress.

Not a fit: Patients with heart failure who do not experience psychological stress or have other unrelated health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies for heart failure hospitalizations by addressing psychological stressors.

How similar studies have performed: Previous research has shown that addressing psychological stress can reduce hospitalization rates in heart failure patients, indicating a promising approach.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.