Investigating the impact of stress on heart failure
Official title: Stress and Congestive Heart Failure: A mechanistic clinical trial
Funded at Yale University · NIH-10892076 · Data updated 2026-11-12
This study is looking at how stress impacts people with heart failure, aiming to find out what triggers stress that can make their symptoms worse, so we can help them manage their condition better and avoid hospital visits.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | July 1, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $727,568 |
| NIH project number | 5R01HL152548-05 |
| Project ID | NIH-10892076 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with heart failure who experience significant psychological stress.
✕Less likely to help
Patients with heart failure who do not experience psychological stress or have other unrelated health conditions may not benefit from this research.
What this research studies
This research focuses on understanding how psychological stress affects patients with heart failure, which is a condition that significantly reduces quality of life and leads to frequent hospital admissions. The study aims to identify stress-related triggers that can worsen heart failure symptoms and lead to hospitalizations. By using advanced technology, such as wireless hemodynamic monitors, the research seeks to capture early signs of heart failure decompensation, allowing for timely interventions. Patients will be monitored to assess the relationship between stress and heart failure events, potentially leading to improved management strategies.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for heart failure hospitalizations by addressing psychological stressors.
How similar studies have gone: Previous research has shown that addressing psychological stress can reduce hospitalization rates in heart failure patients, indicating a promising approach.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Lampert, Rachel — Yale University
- Study coordinator: Lampert, Rachel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.