Investigating the impact of SARS-CoV-2 on Alzheimer's disease risk
Clinical Core
This study is looking at how getting COVID-19 might affect the chances of older adults developing Alzheimer's disease and similar conditions, and it involves 4,300 participants who will share their health history and undergo some tests over three years to help us understand this connection better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10907429 on NIH RePORTER |
What this research studies
This research focuses on understanding how SARS-CoV-2 infection may influence the risk of developing Alzheimer's disease and related dementias. It involves enrolling 4,300 older adults, with a majority having been exposed to COVID-19, and conducting thorough clinical evaluations over a period of 36 months. Participants will undergo medical history assessments, neuropsychological testing, and neurological examinations, along with the collection of blood samples for future analysis. The study aims to gather comprehensive data to explore the connections between viral infections and Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those who have been exposed to SARS-CoV-2, as well as those without such exposure.
Not a fit: Patients who are younger or do not have any exposure to SARS-CoV-2 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the relationship between viral infections and Alzheimer's disease, potentially informing prevention and treatment strategies.
How similar studies have performed: While the specific interactions between SARS-CoV-2 and Alzheimer's disease are still being explored, previous research has shown that viral infections can impact neurological health, suggesting potential for meaningful findings in this area.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: De Erausquin, Gabriel Alejandro — University of Texas Hlth Science Center
- Study coordinator: De Erausquin, Gabriel Alejandro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.