Investigating the impact of probiotics on alcohol-related health issues in people living with HIV.
Administrative, Education, and Analytic Support Core
This study is looking at how drinking alcohol impacts heart health for people living with HIV and whether a special probiotic can help improve gut health and lower inflammation from alcohol use.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10908486 on NIH RePORTER |
What this research studies
This research focuses on how alcohol consumption affects cardiovascular disease risk among individuals living with HIV. It aims to explore whether a specific probiotic can help improve gut health and reduce inflammation caused by alcohol use. By utilizing a multidisciplinary approach, the study will analyze the gut microbiome and metabolic profiles of participants to understand the relationship between alcohol, gut health, and cardiovascular outcomes. Participants may be involved in randomized controlled trials to assess the effectiveness of the probiotic intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who also consume alcohol and are at risk for cardiovascular disease.
Not a fit: Patients who do not consume alcohol or those without HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cardiovascular health and reduced mortality rates among people living with HIV who consume alcohol.
How similar studies have performed: Previous research has shown promising results in using probiotics to improve gut health and reduce inflammation, suggesting potential success for this approach.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Freiberg, Matthew S — Vanderbilt University Medical Center
- Study coordinator: Freiberg, Matthew S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.