Investigating the impact of PFAS on bone health in Hispanic/Latino populations.
Official title: PFAS and bone health over the life course in Hispanic/Latinos: emerging risk factors and underlying mechanisms
Funded at University of Southern California · NIH-11046435 · Data updated 2026-11-12
This study is looking at how certain chemicals called PFAS might affect bone health in Hispanic and Latino people, who are more likely to develop osteoporosis, to help us understand the connection between these chemicals and bone issues throughout different stages of life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | January 3, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $709,575 |
| NIH project number | 1R01ES036253-01A1 |
| Project ID | NIH-11046435 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include Hispanic and Latino individuals, particularly those who are overweight or obese and at risk for osteoporosis.
✕Less likely to help
Patients who are not Hispanic or Latino or those without risk factors for osteoporosis may not benefit from this research.
What this research studies
This research focuses on understanding how exposure to per- and polyfluoroalkyl substances (PFAS) affects bone health in Hispanic and Latino individuals, who are at a higher risk for osteoporosis. The study will analyze data from multiple cohorts over time to assess the effects of PFAS on bone mass and metabolism at different life stages. By utilizing advanced biomarker techniques, the research aims to uncover the biological mechanisms linking PFAS exposure to bone health issues. This comprehensive approach seeks to fill existing gaps in knowledge regarding environmental factors influencing bone health disparities in this population.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for osteoporosis and related bone health issues in Hispanic and Latino communities.
How similar studies have gone: While there is limited research specifically on PFAS and bone health in Latino populations, studies on PFAS exposure and health effects in other groups have shown concerning results, indicating the potential for significant findings in this area.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Chatzi, Vaia Lida — University of Southern California
- Study coordinator: Chatzi, Vaia Lida
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.