Investigating the impact of PFAS chemicals on liver health and developing solutions for contamination.

Southern California Superfund Research and Training Program for PFAS Assessment, Remediation, and Prevention (ShARP)

NIH-funded research University of Southern California · NIH-10939225

This study is looking at how certain chemicals in our water can affect liver health, and it's for anyone interested in understanding the risks of these substances and how we can better protect ourselves and our environment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-10939225 on NIH RePORTER

What this research studies

This research focuses on understanding how poly- and perfluoroalkyl substances (PFAS) contaminate water sources and their effects on liver health. By utilizing advanced techniques, the project aims to evaluate PFAS exposure through human studies and innovative 3D liver models. The research will also develop new methods for detecting PFAS in the environment and create predictive models for groundwater contamination. Patients may benefit from improved understanding and potential interventions for liver diseases linked to PFAS exposure.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals living near contaminated sites or those with liver health concerns potentially linked to PFAS exposure.

Not a fit: Patients who do not reside in areas affected by PFAS contamination or who do not have liver health issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention and treatment strategies for liver diseases associated with PFAS exposure.

How similar studies have performed: Previous research has shown promising results in addressing environmental contaminants and their health impacts, indicating potential for success in this novel approach.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.