Investigating the impact of heart health on cognitive aging in older Hispanic adults

The San Antonio Heart and Mind Study

NIH-funded research University of Texas Hlth Science Center · NIH-11055374

This study is looking at how heart health impacts thinking and memory as we age, especially in older Hispanic adults, and it invites participants to take part in tests and brain scans to help understand why Alzheimer's disease affects this group differently.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Science Center NIH-funded
Lab location1 site (San Antonio, United States)
Project IDNIH-11055374 on NIH RePORTER

What this research studies

This research focuses on understanding how heart health and related diseases affect cognitive aging and the risk of Alzheimer's disease and related dementias in older Hispanic adults. By re-establishing a cohort from a previous study, researchers will invite participants to undergo comprehensive assessments, including cognitive function tests, brain imaging, and biomarker measurements. The study aims to identify the unique factors contributing to disparities in Alzheimer's disease among Hispanic populations, particularly Mexican Americans. Participants will also have the opportunity to contribute to a brain donation program for further research.

Who could benefit from this research

Good fit: Ideal candidates for this research are older Hispanic adults, particularly those with a history of cardiometabolic diseases.

Not a fit: Patients who are younger than 21 years old or do not identify as Hispanic may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and targeted interventions for Alzheimer's disease in older Hispanic adults.

How similar studies have performed: Previous research has shown success in studying the relationship between cardiovascular health and cognitive decline, making this approach promising.

Where this research is happening

San Antonio, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.