Investigating the impact of heart health on cognitive aging in older Hispanic adults
Official title: The San Antonio Heart and Mind Study
Funded at University of Texas Hlth Science Center · NIH-11055374 · Data updated 2026-11-12
This study is looking at how heart health impacts thinking and memory as we age, especially in older Hispanic adults, and it invites participants to take part in tests and brain scans to help understand why Alzheimer's disease affects this group differently.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | July 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $3,535,113 |
| NIH project number | 5R01AG082360-03 |
| Project ID | NIH-11055374 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older Hispanic adults, particularly those with a history of cardiometabolic diseases.
✕Less likely to help
Patients who are younger than 21 years old or do not identify as Hispanic may not receive benefit from this research.
What this research studies
This research focuses on understanding how heart health and related diseases affect cognitive aging and the risk of Alzheimer's disease and related dementias in older Hispanic adults. By re-establishing a cohort from a previous study, researchers will invite participants to undergo comprehensive assessments, including cognitive function tests, brain imaging, and biomarker measurements. The study aims to identify the unique factors contributing to disparities in Alzheimer's disease among Hispanic populations, particularly Mexican Americans. Participants will also have the opportunity to contribute to a brain donation program for further research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and targeted interventions for Alzheimer's disease in older Hispanic adults.
How similar studies have gone: Previous research has shown success in studying the relationship between cardiovascular health and cognitive decline, making this approach promising.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Satizabal, Claudia L — University of Texas Hlth Science Center
- Study coordinator: Satizabal, Claudia L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.