Investigating the impact of false positive results in lung cancer screening
Lung Cancer Screening: Cumulative Risk and Multilevel Impact of False Positive Findings
This study is looking at how false alarms from lung cancer screenings can affect patients and the healthcare system, and it aims to find ways to reduce these false alarms so that everyone can have better conversations about their health and get the most out of their screenings.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10980096 on NIH RePORTER |
What this research studies
This research focuses on understanding the effects of false positive findings in lung cancer screening using low-dose computed tomography (LDCT). It aims to assess the burden these false positives place on patients, healthcare providers, and the healthcare system as a whole. By analyzing data from multiple rounds of screening, the study seeks to identify factors that contribute to false positives and develop strategies to minimize their occurrence. This will help improve patient-clinician discussions and optimize the benefits of lung cancer screening.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 50-80 who are current or former smokers with a significant smoking history.
Not a fit: Patients who do not meet the age or smoking history criteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved lung cancer screening protocols that reduce unnecessary anxiety and invasive procedures for patients.
How similar studies have performed: Previous research has indicated the challenges associated with false positives in cancer screening, suggesting that addressing this issue could lead to significant improvements in patient care.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Henderson, Louise — Univ of North Carolina Chapel Hill
- Study coordinator: Henderson, Louise
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.