NIH-funded research R21 grant

Investigating the impact of COVID-19 on mortality across different birth cohorts and races

Official title: COVID-19 and Cohort Longevity: Causal Estimates from a Cohort Discontinuity Design

Funded at University of Pennsylvania · NIH-11091645 · Data updated 2026-11-12

This study looks at how COVID-19 has changed death rates for different groups of people in France and the U.S., especially comparing men and women and different races, to better understand the pandemic's impact on survival rates.

More COVID-19 research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startJune 1, 2024
Project endMarch 31, 2026
Funding year2025
Award (this year)$199,376
NIH project number5R21AG086923-02
Project IDNIH-11091645 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals from specific birth cohorts in the U.S. and France, particularly those who identify as Black or White.

Less likely to help

Patients who do not belong to the specified birth cohorts or racial groups may not receive direct benefits from this research.

What this research studies

This research examines how COVID-19 has affected the mortality rates of specific birth cohorts in both France and the United States, focusing on differences between males and females as well as racial disparities among Americans. By utilizing a novel cohort discontinuity design, the study aims to provide causal estimates of the pandemic's impact on all-cause mortality. The research will analyze secondary data from vital registers to ensure high-quality and detailed insights into mortality trends. This approach will help clarify how the pandemic has influenced survival rates and whether it has reversed progress made prior to the pandemic.

Why it matters

Potential benefit: If successful, this research could provide critical insights into the long-term effects of COVID-19 on mortality, informing public health strategies and interventions.

How similar studies have gone: Previous research has successfully utilized cohort analysis to study mortality trends, making this approach both relevant and promising.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Guillot, Michel — University of Pennsylvania
  • Study coordinator: Guillot, Michel

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.