Investigating the impact of COVID-19 on cognitive decline in older adults
Official title: Longitudinal Epidemiology
Funded at University of Texas Hlth Science Center · NIH-10907432 · Data updated 2026-11-12
This study is looking at how COVID-19 might affect thinking and memory in adults over 60, especially those at risk for Alzheimer's, to help us understand the long-term effects and find ways to protect brain health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $502,764 |
| NIH project number | 5U19AG076581-02 |
| Project ID | NIH-10907432 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 60 years old, particularly those with a history of COVID-19 or at risk for Alzheimer's disease.
✕Less likely to help
Patients under 60 years old or those without a history of COVID-19 or Alzheimer's-related conditions may not benefit from this research.
What this research studies
This research focuses on understanding how SARS-CoV-2 infection may lead to cognitive impairment in adults over 60 years old, particularly those at risk for Alzheimer's disease and related dementias. The study will involve a large international consortium that collects and analyzes clinical, biomarker, genomic, and neuroimaging data over a period of 36 months. Participants will be followed to assess the long-term effects of COVID-19 on cognitive health and identify factors that may influence resilience or risk of decline. The research aims to provide insights into the relationship between COVID-19 and Alzheimer's disease progression.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cognitive decline in older adults post-COVID-19.
How similar studies have gone: Previous studies have indicated a link between COVID-19 and cognitive impairment, suggesting that this research builds on established findings rather than being entirely novel.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: De Erausquin, Gabriel Alejandro — University of Texas Hlth Science Center
- Study coordinator: De Erausquin, Gabriel Alejandro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.