Investigating the impact of COVID-19 cytokine storms on kidney health
Covid 19 cytokine storm
This study is looking at how the immune response during COVID-19 can affect kidney health, especially in patients who are hospitalized, and aims to find new ways to help treat kidney problems caused by the virus.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10897320 on NIH RePORTER |
What this research studies
This research focuses on understanding how the cytokine storm associated with COVID-19 affects kidney function, particularly through the development of proteinuria in hospitalized patients. The team will utilize novel 'cytokine cocktail' models to study the immune response and its impact on kidney cells in both animal models and laboratory settings. By examining the interactions between various cytokines and kidney receptors, the research aims to identify potential treatment strategies for COVID-related kidney disease. Patients may benefit from insights gained into the mechanisms of kidney damage and potential therapeutic interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include hospitalized patients with COVID-19 who are experiencing kidney issues, such as proteinuria.
Not a fit: Patients with kidney disease unrelated to COVID-19 or those not hospitalized may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients suffering from kidney complications due to COVID-19.
How similar studies have performed: Previous research on cytokine storms in other viral infections has shown promise, suggesting that this approach may yield valuable insights.
Where this research is happening
Chicago, United States
- Rush University Medical Center — Chicago, United States (Active)
Researchers
- Principal investigator: Chugh, Sumant Singh — Rush University Medical Center
- Study coordinator: Chugh, Sumant Singh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.