Investigating the impact of childhood adversity on multiple sclerosis in minority populations
Official title: Childhood Adversity Research Effort in Multiple Sclerosis (CARE.in.MS)
Funded at New York University School of Medicine · NIH-11024781 · Data updated 2026-11-12
This study is looking at how tough experiences in childhood can impact the health of people with multiple sclerosis, especially in minority communities, and it aims to work closely with those affected to make sure their voices and needs are heard.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 9, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $742,352 |
| NIH project number | 1R01NS139999-01 |
| Project ID | NIH-11024781 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with multiple sclerosis who identify as members of minority populations and have experienced childhood adversity.
✕Less likely to help
Patients without a diagnosis of multiple sclerosis or those who do not identify with the targeted minority populations may not receive benefit from this research.
What this research studies
This research focuses on understanding how childhood adversity affects health outcomes in individuals with multiple sclerosis (MS), particularly among minority populations. By collaborating with individuals who have MS and come from vulnerable communities, the study aims to explore the connections between early life challenges and the progression of MS. The research employs a culturally-informed approach, utilizing community engagement and multidisciplinary methods to develop effective research tools and analyze data. Participants will help shape the study, ensuring that it addresses the specific needs and experiences of those affected.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes and tailored interventions for individuals with multiple sclerosis who have experienced childhood adversity.
How similar studies have gone: Other research has shown that addressing social determinants of health, such as childhood adversity, can significantly impact health outcomes in various populations, suggesting a promising avenue for this study.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Krupp, Lauren B — New York University School of Medicine
- Study coordinator: Krupp, Lauren B
Related research
Other NIH-funded projects on the same topics.
-
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-
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-
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-
Astrocyte exosomes as aging biomarkers and drivers of MS progression
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-
Promoting brain repair in MS with a natural compound that nudges neural stem cells
A researcher is testing a natural-product–based compound that may help people with multiple sclerosis repair nerve damage by guiding brain stem cells to become neurons and myelin-producing cells.
-
Targeted B cell tolerance therapy for multiple sclerosis using Ace-DEX microparticles
A new therapy using tiny biopolymer particles given through the vein aims to retrain B cells to tolerate the immune system in people with multiple sclerosis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.