Investigating the impact of alcohol use on health in people living with HIV
Alcohol-Associated Syndemic and Microbiome Evaluation and Targeted Treatment in Persons Living with HIV
This study is looking at how heavy drinking, HIV, depression, and smoking can affect your health, especially your gut health, and it will explore whether taking probiotics and prebiotics can help improve your gut and reduce inflammation for people dealing with these issues.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10911956 on NIH RePORTER |
What this research studies
This research focuses on understanding how hazardous drinking interacts with HIV and other conditions like depression and smoking to increase health risks. It examines the role of the gastrointestinal microbiome in this interaction, particularly how changes in gut bacteria can lead to inflammation and cardiovascular disease. The study aims to explore the potential benefits of using probiotics and prebiotics to improve gut health and reduce inflammation in individuals affected by this syndemic. Patients may be involved in interventions that assess the effectiveness of these treatments over a period of weeks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who engage in hazardous drinking and may also experience depression or smoking-related issues.
Not a fit: Patients who do not have HIV or do not engage in hazardous drinking may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for individuals living with HIV who also struggle with alcohol use and related conditions.
How similar studies have performed: Previous research has shown that probiotics can positively affect gut health in individuals with alcohol use disorder, suggesting potential for success in this study.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Chichetto, Natalie E — University of Florida
- Study coordinator: Chichetto, Natalie E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.