Investigating the impact of a special fish oil on eye health and disease

Elucidating the Role of Very-long-chain Polyunsaturated Fatty Acids in Retinal Health and Disease

NIH-funded research University of Utah · NIH-11043157

This study is looking at a new fish oil supplement that might help improve heart health and protect your vision, especially for those at risk of age-related macular degeneration, and it invites patients to see if this supplement can make a difference for their eye health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11043157 on NIH RePORTER

What this research studies

This research explores how a novel fish oil supplement, rich in very-long-chain polyunsaturated fatty acids (VLCPUFAs), can affect heart health and vision. The study aims to understand the role of these specific fatty acids in the body, particularly in the retina, and how they may help prevent or slow down age-related macular degeneration (AMD). By examining the effects of VLCPUFAs on visual function and cardiometabolic risk factors, the research seeks to provide insights into potential treatments for conditions that lead to blindness. Patients may be involved in trials to assess the effectiveness of this supplement in improving their eye health.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults at risk for age-related macular degeneration or those experiencing early signs of vision loss.

Not a fit: Patients with conditions unrelated to retinal health or those who are not at risk for age-related macular degeneration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new dietary interventions that improve vision and reduce the risk of blindness in aging populations.

How similar studies have performed: Previous research has shown that omega-3 fatty acids can have beneficial effects on eye health, but the specific role of VLCPUFAs in treating AMD is still being explored.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.