Investigating the immune response to COVID-19 through antibody testing

Frederick National Laboratory for Cancer Research (FNLCR) Center for SARS-CoV-2 Serological Sciences

NIH-funded research Leidos Biomedical Research, INC. · NIH-10497644

This study is looking at how our immune system fights COVID-19 by creating better tests to check for antibodies, which can help people understand their protection against the virus after infection or vaccination.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLeidos Biomedical Research, INC. NIH-funded
Lab location1 site (Frederick, United States)
Project IDNIH-10497644 on NIH RePORTER

What this research studies

This research focuses on understanding how the immune system responds to COVID-19 by developing advanced tests to detect antibodies against the virus. The project aims to create highly specific and sensitive serological assays, including ELISAs and point-of-care tests, to expand national testing capabilities. By studying the immune responses in individuals who have been infected or vaccinated, the research seeks to identify correlates of protection and improve our understanding of immunity to SARS-CoV-2. Patients may benefit from enhanced testing and insights into their immune status regarding COVID-19.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals who have been infected with SARS-CoV-2 or vaccinated against COVID-19.

Not a fit: Patients who have not been exposed to SARS-CoV-2 or have not received a COVID-19 vaccine may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved testing methods and a better understanding of immunity to COVID-19, ultimately aiding in public health responses.

How similar studies have performed: Previous research has shown success in developing serological assays for other viruses, indicating potential for similar advancements in COVID-19 testing.

Where this research is happening

Frederick, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancerDisorderDisease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.