Investigating the immune environment of ovarian cancer tumors to improve survival predictions for patients

Who could benefit from this research

What this research studies

This research focuses on analyzing the tumor immune microenvironment in women with ovarian cancer using advanced imaging techniques and statistical models. By employing multiplex immunofluorescence microscopy and automated image analysis, the study aims to uncover the spatial distribution of immune cells within tumors, which is crucial for understanding their role in cancer progression. The researchers will develop new statistical methods to analyze this data and create an immunoscore that can predict patient survival outcomes. The study will utilize data from approximately 2,500 ovarian cancer patients to validate these findings and improve treatment strategies.

Why it matters

Where this research is happening

• Children's Mercy Hosp (Kansas City, Mo)
  Kansas City, United States Active

Researchers

• Principal investigator: Fridley, Brooke L — Children's Mercy Hosp (Kansas City, Mo)
• Study coordinator: Fridley, Brooke L

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.