Investigating the heart risks of having both sleep apnea and COPD.
The cardiovascular consequences of sleep apnea plus COPD (Overlap syndrome)
This study is looking at how having both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) affects heart health, so if you have either condition or both, your participation could help us understand the risks and find better treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10912766 on NIH RePORTER |
What this research studies
This research focuses on understanding the cardiovascular risks associated with the overlap of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), known as overlap syndrome (OVS). The study will compare cardiovascular risk markers in patients with OSA, COPD, and those with both conditions to determine how OVS affects heart health. Researchers will utilize advanced imaging techniques and blood tests to gather data on heart function and specific biomarkers. The goal is to clarify the mechanisms behind the increased cardiovascular risks in patients with OVS and explore potential treatment benefits.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with both obstructive sleep apnea and chronic obstructive pulmonary disease.
Not a fit: Patients who do not have either obstructive sleep apnea or chronic obstructive pulmonary disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that reduce cardiovascular risks for patients with overlap syndrome.
How similar studies have performed: Previous research has shown promising results in understanding the cardiovascular impacts of sleep apnea and COPD, but this specific overlap syndrome approach is relatively novel.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Malhotra, Atul — University of California, San Diego
- Study coordinator: Malhotra, Atul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.