Investigating the health impacts of HIV treatments on children and young adults

Pediatric HIV/AIDS Cohort Study (PHACS) 2020

NIH-funded research Harvard School of Public Health · NIH-10897160

This study is looking at how taking HIV medications during pregnancy affects the long-term health of children and young adults who were exposed to HIV before birth, whether they have HIV or not, so we can better understand the safety of these treatments.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionHarvard School of Public Health NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10897160 on NIH RePORTER

What this research studies

This research focuses on understanding the long-term health effects of antiretroviral medications (ARVs) on children and young adults who were exposed to HIV in utero. It involves monitoring a large cohort of infants, children, and adolescents to assess their health outcomes as they transition into adulthood. The study aims to gather data on both those living with perinatally acquired HIV and those who were exposed but uninfected, providing insights into the safety and efficacy of current HIV treatments. By following these individuals over time, the research seeks to identify any potential health issues related to early exposure to ARVs.

Who could benefit from this research

Good fit: Ideal candidates for this research include children and young adults who were either born with HIV or were exposed to HIV in utero.

Not a fit: Patients who are not affected by HIV or were not exposed to HIV in utero may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health management strategies for children and young adults living with or affected by HIV.

How similar studies have performed: Previous research has shown success in monitoring health outcomes in similar cohorts, indicating the potential for meaningful findings in this study.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.