NIH-funded research R01 grant

Investigating the health effects of wildfire smoke exposure in urban areas

Official title: Wildland Urban Interface Exposure Toxicity in Cells, Animals, and Humans

Funded at Univ of North Carolina Chapel Hill · NIH-11058523 · Data updated 2026-11-12

This study is looking at how breathing in smoke from wildfires can affect people’s health, especially those living in cities close to forests, by checking how it impacts conditions like asthma and bronchitis, so we can better understand the risks and help keep everyone safe.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startMarch 20, 2024
Project endDecember 31, 2028
Funding year2025
Award (this year)$677,273
NIH project number5R01ES035878-02
Project IDNIH-11058523 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals living in areas prone to wildfires who suffer from respiratory conditions such as asthma or chronic obstructive pulmonary disease.

Less likely to help

Patients who do not live in wildfire-prone areas or do not have respiratory conditions may not receive direct benefits from this research.

What this research studies

This research focuses on understanding how exposure to wildfire smoke affects human health, particularly in urban areas near wildland interfaces. The team will study the impacts of smoke on respiratory conditions such as asthma and bronchitis by using advanced methods to measure harmful chemicals in simulated wildfire scenarios. They will conduct experiments on cells, animals, and humans to identify biological changes and health risks associated with smoke exposure. The goal is to develop predictive models for health risks related to wildfire smoke exposure.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of health risks associated with wildfire smoke exposure, ultimately improving patient care and public health responses.

How similar studies have gone: Previous research has shown that exposure to wildfire smoke can significantly impact respiratory health, indicating that this study builds on established findings while exploring new methodologies.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Rager, Julia — Univ of North Carolina Chapel Hill
  • Study coordinator: Rager, Julia

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.