Investigating the health effects of PFAS mixtures in drinking water

Spatial and Tensor Methods for Estimating the Health Effects of PFAS Mixtures

NIH-funded research North Carolina State University Raleigh · NIH-11050456

This study is looking at how harmful chemicals called PFAS in drinking water might affect your health, using data from Medicare and health records to better understand the connection between these chemicals and health problems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorth Carolina State University Raleigh NIH-funded
Lab location1 site (Raleigh, United States)
Project IDNIH-11050456 on NIH RePORTER

What this research studies

This research focuses on understanding how mixtures of perfluoroalkyl and polyfluoroalkyl substances (PFAS), which are harmful chemicals found in drinking water, affect health outcomes. By utilizing advanced statistical methods and data from nationwide Medicare beneficiaries and electronic health records in North Carolina, the project aims to identify the causal relationships between PFAS exposure and various health issues. The study addresses challenges such as spatial dependence and bias in observational data to provide a clearer picture of PFAS health impacts.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have been exposed to PFAS through drinking water, particularly those in areas with known contamination.

Not a fit: Patients who have not been exposed to PFAS or those with unrelated health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved public health guidelines and interventions to reduce the harmful effects of PFAS in drinking water.

How similar studies have performed: Previous research has shown success in using similar statistical methods to analyze health outcomes related to environmental exposures, indicating a promising approach.

Where this research is happening

Raleigh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.