NIH-funded research R01 grant

Investigating the health effects of micro-nanoplastics in the body

Official title: Intestinal uptake, translocation, biodistribution, and toxicity of ingested environmentally relevant micro-nanoplastics (MNPs) and the role of inflammation using advanced cellular and in vivo models

Funded at Rutgers Biomedical and Health Sciences · NIH-10996862 · Data updated 2026-11-12

This study is looking at how tiny plastic particles, called micro-nanoplastics, get into our bodies and what effects they might have on our health, so we can better understand the risks they pose to everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers Biomedical and Health Sciences
NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project startJuly 15, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$637,553
NIH project number1R01ES036043-01A1
Project IDNIH-10996862 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have been exposed to environments with high levels of micro-nanoplastics, such as those living near industrial areas or consuming contaminated food.

Less likely to help

Patients who have no history of exposure to micro-nanoplastics or related environmental contaminants may not benefit from this research.

What this research studies

This research explores how micro-nanoplastics (MNPs), tiny plastic particles found in our environment and food, are absorbed by the body and their potential health impacts. The study will use advanced cellular and animal models to track how these particles move through the body, where they accumulate, and how they may cause inflammation or toxicity. By understanding these processes, the research aims to fill critical gaps in knowledge regarding the risks associated with MNP exposure.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of health risks associated with micro-nanoplastics exposure.

How similar studies have gone: While there is emerging research on the effects of microplastics, this specific investigation into their biodistribution and toxicity in humans is relatively novel and untested.

Where this research is happening

  • Rutgers Biomedical and Health Sciences
    Newark, United States
    Active

Researchers

  • Principal investigator: Demokritou, Philip — Rutgers Biomedical and Health Sciences
  • Study coordinator: Demokritou, Philip

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.