Investigating the health effects of metals in Native American communities

Health Effects of Metals in Native American Communities: A Longitudinal Multi-omics Study

NIH-funded research Columbia University Health Sciences · NIH-10877760

This study is looking at how being around metals like arsenic and uranium for a long time affects the health of Native American communities, especially in relation to heart and diabetes issues, by using data from the Strong Heart Study collected over 30 years and inviting new participants to join.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10877760 on NIH RePORTER

What this research studies

This research focuses on understanding how long-term exposure to metals like arsenic and uranium affects the health of Native American populations, particularly concerning cardiometabolic diseases such as diabetes and cardiovascular disease. By analyzing data collected over 30 years from participants in the Strong Heart Study, the research aims to uncover the lasting impacts of these exposures on health outcomes. The study will involve both historical data and new participant recruitment to explore the joint effects of these metals and their biological mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research include Native American individuals, particularly those with a history of exposure to arsenic or uranium, and those with or at risk for cardiometabolic diseases.

Not a fit: Patients who do not belong to Native American communities or who have not been exposed to the metals being studied may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health interventions and policies that address the unique health challenges faced by Native American communities.

How similar studies have performed: Previous studies have shown significant associations between metal exposure and health outcomes in similar populations, indicating that this research builds on established findings.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiometabolic DiseaseCardiometabolic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.