Investigating the health effects of 1,4-dioxane exposure
Evaluation of novel markers of exposure and biological response to 1,4-dioxane
This study is looking at how exposure to a chemical called 1,4-dioxane in drinking water might affect health, especially for people living in areas like Long Island and the Cape Fear River Watershed, by checking blood samples to find out more about its potential risks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10868586 on NIH RePORTER |
What this research studies
This research focuses on understanding the health impacts of 1,4-dioxane, a chemical found in drinking water that may pose cancer risks. The study will evaluate exposure levels and biological responses in communities with high contamination, particularly in Long Island, New York, and the Cape Fear River Watershed in North Carolina. Researchers will collect and analyze blood samples to identify novel biological markers associated with exposure to this chemical and its co-occurring contaminants. The goal is to fill the gap in human health data related to 1,4-dioxane exposure and its potential risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older living in areas with known contamination of 1,4-dioxane in their drinking water.
Not a fit: Patients who do not reside in contaminated areas or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved public health guidelines and interventions to reduce exposure to harmful chemicals in drinking water.
How similar studies have performed: Previous research has shown that evaluating exposure to environmental contaminants can yield significant insights into public health risks, indicating that this approach has potential for success.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Deziel, Nicole — Yale University
- Study coordinator: Deziel, Nicole
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.