Investigating the gut microbiome's role in liver disease and PTSD among US Veterans

Who could benefit from this research

What this research studies

This research focuses on understanding how post-traumatic stress disorder (PTSD) affects liver health and gut microbiome in US Veterans. It examines the connections between PTSD, liver cirrhosis, and cognitive dysfunction, exploring how changes in gut bacteria and inflammation may influence these conditions. By analyzing stool samples and other biological markers, the study aims to uncover the underlying mechanisms linking gut health to brain function and liver disease. The findings could lead to new treatment strategies that target the gut microbiome to improve health outcomes for affected Veterans.

Why it matters

Where this research is happening

• VA Veterans Administration Hospital
  Richmond, United States Active

Researchers

• Principal investigator: Bajaj, Jasmohan S — VA Veterans Administration Hospital
• Study coordinator: Bajaj, Jasmohan S

Related research

Other NIH-funded projects on the same topics.

• Gut health and PTSD in veterans with inflammatory bowel disease

  A study explores how the gut microbiome and chronic stress from military experiences may influence inflammatory bowel disease in veterans.

  NIH research Veterans Health Administration · Nashville, United States · NIH-11333100

• Understanding Gut Health in Veterans with Deployment-Related GI and Liver Conditions

  This project explores how the gut microbiome and PTSD might be connected to inflammatory bowel disease and other digestive issues in Veterans.

  NIH research Veterans Health Administration · Nashville, United States · NIH-11132581

• Investigating the gut microbiome's role in gastrointestinal and liver diseases in veterans with PTSD.

  This study is looking at how the bacteria in your gut might affect stomach and liver problems in veterans, especially those with PTSD, and it invites you to share your gut health samples to help us understand these connections better.

  NIH research Veterans Health Administration · Nashville, United States · NIH-10830928

• Gut microbes and diarrhea risk in Gulf War veterans

  This project looks at whether changes in gut microbes explain why Gulf War and other deployed veterans get frequent diarrhea and related gut problems.

  NIH research Jesse Brown VA Medical Center · Chicago, United States · NIH-11213927

• Gut microbiome, fiber, and short-chain fatty acids in Veterans with Gulf War Illness

  This project tests whether Veterans with Gulf War Illness who have gut problems have lower levels of helpful gut bacteria and short-chain fatty acids, and whether eating more fiber relates to fewer digestive symptoms.

  NIH research Wm S. Middleton Memorial Veterans Hosp · Madison, United States · NIH-11132615

• Understanding how gut bacteria affect gastrointestinal diseases in veterans.

  This study is looking at how the bacteria in the gut might affect stomach and liver problems in veterans, especially those with Gulf War Illness, to find new ways to help improve their health and ease symptoms like diarrhea and inflammatory bowel diseases.

  NIH research Jesse Brown VA Medical Center · Chicago, United States · NIH-10950290

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.