Investigating the gut microbiome's role in liver disease and PTSD among US Veterans
BCCMA: Targeting Gut Microbiome in Gastrointestinal and Liver Diseases in US Veterans; CMA4: At the Crossroads of the Gut Microbiome, Cirrhosis, and PTSD
This study is looking at how PTSD might impact the health of veterans' livers and gut bacteria, hoping to find new ways to help improve their overall health by understanding the connections between these areas.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Veterans Administration Hospital NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10975928 on NIH RePORTER |
What this research studies
This research focuses on understanding how post-traumatic stress disorder (PTSD) affects liver health and gut microbiome in US Veterans. It examines the connections between PTSD, liver cirrhosis, and cognitive dysfunction, exploring how changes in gut bacteria and inflammation may influence these conditions. By analyzing stool samples and other biological markers, the study aims to uncover the underlying mechanisms linking gut health to brain function and liver disease. The findings could lead to new treatment strategies that target the gut microbiome to improve health outcomes for affected Veterans.
Who could benefit from this research
Good fit: Ideal candidates for this research are US Veterans diagnosed with both PTSD and liver cirrhosis.
Not a fit: Patients without PTSD or liver cirrhosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that improve cognitive function and liver health in Veterans suffering from PTSD and cirrhosis.
How similar studies have performed: Previous studies have shown promising results in understanding the gut-brain-liver axis, indicating potential for success in this novel approach.
Where this research is happening
Richmond, United States
- VA Veterans Administration Hospital — Richmond, United States (Active)
Researchers
- Principal investigator: Bajaj, Jasmohan S — VA Veterans Administration Hospital
- Study coordinator: Bajaj, Jasmohan S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.