Investigating the gut microbiome's role in gastrointestinal and liver diseases in veterans with PTSD.
Official title: BCCMA: Targeting Gut-Microbiome in Veterans Deployment Related Gastrointestinal and Liver Diseases: Dysbiosis, PTSD, and Epithelial and Immune Biology in Inflammatory Bowel Disease in Veterans
Funded at Veterans Health Administration · NIH-10830928 · Data updated 2026-11-12
This study is looking at how the bacteria in your gut might affect stomach and liver problems in veterans, especially those with PTSD, and it invites you to share your gut health samples to help us understand these connections better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| NIH project number | 5I01CX002473-02 |
| Project ID | NIH-10830928 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans experiencing gastrointestinal issues or liver diseases, particularly those with a diagnosis of PTSD.
✕Less likely to help
Patients without a history of military service or those not experiencing gastrointestinal or liver diseases may not benefit from this research.
What this research studies
This research focuses on understanding how the gut microbiome affects gastrointestinal and liver diseases in veterans, particularly those with post-traumatic stress disorder (PTSD). By examining the relationship between chronic stress, gut health, and inflammatory bowel disease (IBD), the study aims to uncover mechanisms that contribute to higher rates of these conditions among veterans. The research involves collaborative projects that will analyze gut microbiome samples and assess their impact on health outcomes. Patients may be asked to provide samples and participate in assessments to help identify potential links between their gut health and their experiences related to military service.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for gastrointestinal and liver diseases in veterans.
How similar studies have gone: Previous research has shown promising results in understanding the gut microbiome's role in various diseases, suggesting that this approach could yield valuable insights for veterans' health.
Where this research is happening
-
Veterans Health Administration
Nashville, United States Active
Researchers
- Principal investigator: Wilson, Keith T. — Veterans Health Administration
- Study coordinator: Wilson, Keith T.
Related research
Other NIH-funded projects on the same topics.
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Gut health and PTSD in veterans with inflammatory bowel disease
A study explores how the gut microbiome and chronic stress from military experiences may influence inflammatory bowel disease in veterans.
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Understanding Gut Health in Veterans with Deployment-Related GI and Liver Conditions
This project explores how the gut microbiome and PTSD might be connected to inflammatory bowel disease and other digestive issues in Veterans.
-
Investigating the gut microbiome's role in liver disease and PTSD among US Veterans
This study is looking at how PTSD might impact the health of veterans' livers and gut bacteria, hoping to find new ways to help improve their overall health by understanding the connections between these areas.
-
Gut microbes and diarrhea risk in Gulf War veterans
This project looks at whether changes in gut microbes explain why Gulf War and other deployed veterans get frequent diarrhea and related gut problems.
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Gut microbiome, fiber, and short-chain fatty acids in Veterans with Gulf War Illness
This project tests whether Veterans with Gulf War Illness who have gut problems have lower levels of helpful gut bacteria and short-chain fatty acids, and whether eating more fiber relates to fewer digestive symptoms.
-
Using diet to prevent Clostridioides difficile infections
This study is looking at how eating more fiber and less fat might help people, especially those with cancer, avoid infections from C. diff by changing the bacteria in their gut and how their bodies respond to antibiotics.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.