Investigating the genetics of bipolar disorder in Asian populations
4/4 Asian Bipolar Genetics Network (A-BIG-NET)
This study is looking at the genetic factors that might play a role in bipolar disorder, specifically for people from East and South Asian backgrounds, by gathering information from thousands of individuals to help improve our understanding of the condition and support better health for these communities.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Taiwan University NIH-funded |
| Lab location | 1 site (Taipei, Taiwan) |
| Project ID | NIH-10910913 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors associated with bipolar disorder (BP) specifically in East and South Asian populations. By forming the Asian Bipolar Genetics Network (A-BIG-NET), the study aims to collect genetic data from 27,500 individuals with bipolar disorder and 16,000 controls, along with detailed information about their environmental stressors and phenotypic characteristics. The approach includes advanced genetic sequencing techniques to uncover both common and rare genetic variants that may contribute to BP, addressing the gaps left by previous studies that primarily involved European ancestry. This comprehensive analysis aims to enhance our understanding of BP and reduce health disparities in Asian populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals of Asian descent who have been diagnosed with bipolar disorder.
Not a fit: Patients who do not have bipolar disorder or are not of Asian descent may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for individuals with bipolar disorder in Asian communities.
How similar studies have performed: Previous genetic studies in other populations have shown success in identifying genetic variants associated with psychiatric disorders, suggesting that this approach could yield valuable insights for Asian populations as well.
Where this research is happening
Taipei, Taiwan
- National Taiwan University — Taipei, Taiwan (Active)
Researchers
- Principal investigator: Kuo, Po Hsiu — National Taiwan University
- Study coordinator: Kuo, Po Hsiu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.