Investigating the genetics of a vision loss condition called central serous chorioretinopathy.
Genetics of central serous chorioretinopathy and choroidal thickening
This study is looking at how our genes might affect central serous chorioretinopathy (CSC), a condition that can cause vision problems, and it’s for anyone interested in understanding more about the genetic links to this eye issue and its connection to age-related vision changes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11077874 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors associated with central serous chorioretinopathy (CSC), a condition that can lead to progressive vision loss. The study aims to identify genetic variations linked to CSC and the thickness of the choroid, which is a layer of blood vessels in the eye. By examining these genetic associations, researchers hope to uncover new insights into the mechanisms of CSC and its relationship with age-related macular degeneration. The principal investigator will receive training in statistical genetics and advanced imaging techniques to enhance patient recruitment and data analysis.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals diagnosed with central serous chorioretinopathy or those with a family history of the condition.
Not a fit: Patients with other unrelated eye conditions or those who do not have a genetic predisposition to CSC may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential new treatments for patients suffering from central serous chorioretinopathy.
How similar studies have performed: Previous research has shown promising results in identifying genetic factors related to age-related macular degeneration, suggesting that this approach may yield valuable insights for CSC as well.
Where this research is happening
Boston, United States
- Massachusetts Eye and Ear Infirmary — Boston, United States (Active)
Researchers
- Principal investigator: Rossin, Elizabeth Jeffries — Massachusetts Eye and Ear Infirmary
- Study coordinator: Rossin, Elizabeth Jeffries
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.