Investigating the genetic mixing of human and livestock parasites in Africa
Genomic consequences of schistosome hybridization
This study is looking at how two types of parasites, one that affects livestock and another that infects people, might mix together and what that could mean for treating diseases and preventing drug resistance, especially in West Africa.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Biomedical Research Institute NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10912455 on NIH RePORTER |
What this research studies
This research explores how hybridization between the Schistosoma bovis parasite, which affects livestock, and the Schistosoma haematobium parasite, which infects humans, may influence disease management and drug resistance. By conducting genetic analyses in the laboratory and examining samples from regions in West Africa, the study aims to clarify the extent of hybridization and its implications for human health. The researchers will utilize advanced genomic techniques to identify and characterize the genetic material shared between these parasites, providing insights into their evolutionary history and potential impacts on disease transmission.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living in West Africa who are affected by schistosomiasis or are at risk of infection.
Not a fit: Patients who do not reside in areas where schistosomiasis is prevalent or who are not infected with the parasites may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing schistosomiasis and reducing drug resistance in affected populations.
How similar studies have performed: Previous research has indicated the potential for hybridization between these parasite species, but this study aims to provide more definitive evidence and insights into the genetic implications.
Where this research is happening
San Antonio, United States
- Texas Biomedical Research Institute — San Antonio, United States (Active)
Researchers
- Principal investigator: Anderson, Tim J — Texas Biomedical Research Institute
- Study coordinator: Anderson, Tim J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.