Investigating the genetic factors of Alzheimer's disease in Koreans
Genetic Studies of Alzheimer Disease in Koreans
This study is looking at how genes might play a role in Alzheimer's disease specifically for people in Korea, as they haven't been studied much before, and it will follow participants over time to see how these genetic factors affect the disease.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10691356 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic basis of Alzheimer's disease (AD) specifically in the Korean population, which has been underrepresented in previous studies. By analyzing genetic samples from individuals with AD and healthy controls, the researchers aim to identify both common and rare genetic variants that may contribute to the disease. The study will utilize a longitudinal approach, tracking participants over time to assess the impact of these genetic factors on disease progression. This research seeks to fill the gap in knowledge regarding how genetics influence AD in Koreans, a group with a unique genetic profile.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals of Korean descent who are either diagnosed with Alzheimer's disease or are healthy controls.
Not a fit: Patients who do not identify as Korean or who have other forms of dementia unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new treatments for Alzheimer's disease tailored to the Korean population.
How similar studies have performed: Previous research has successfully identified genetic variants associated with Alzheimer's disease in other ethnic groups, suggesting that this approach could yield valuable insights for the Korean population as well.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Farrer, Lindsay a. — Boston University Medical Campus
- Study coordinator: Farrer, Lindsay a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.