Investigating the genetic causes of Müllerian anomalies in females.
The Genetics and penetrance of the Mullerian Anomalies: Addressing the Challenges of the bench to bedside gap.
This study is looking into the genetic causes of Müllerian anomalies, which are conditions that affect how the female reproductive system develops, to help doctors better diagnose and treat those who have these issues.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10668122 on NIH RePORTER |
What this research studies
This research aims to explore the genetic factors contributing to Müllerian anomalies (MAs), which are common developmental abnormalities affecting the female reproductive system. By collaborating with experts in pediatric gynecology, genomics, and developmental biology, the project will analyze genetic data and population phenotypes to better understand these conditions. The goal is to bridge the gap between basic science and clinical applications, ultimately improving diagnosis and treatment options for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research include females aged 12-20 who have been diagnosed with Müllerian anomalies or related reproductive health issues.
Not a fit: Patients who do not have Müllerian anomalies or are outside the age range of 12-20 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of Müllerian anomalies, improving reproductive health outcomes for women.
How similar studies have performed: Previous research has indicated the potential for genetic studies to uncover important insights into congenital anomalies, suggesting that this approach may yield valuable findings.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Vash-Margita, Alla — Yale University
- Study coordinator: Vash-Margita, Alla
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.