Investigating the genetic causes of endometriosis
Microphysiological modeling of Endometriosis
['FUNDING_R01'] · NORTHWESTERN UNIVERSITY AT CHICAGO · NIH-10935984
This study is looking at endometriosis, a condition that causes pain and can affect fertility in women and girls, by using blood samples to create special cells that help researchers learn more about how these cells work with the immune system, with the hope of finding better treatments and understanding for those affected.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY AT CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10935984 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding endometriosis, a condition affecting many women and girls that causes chronic pain and infertility. By using advanced technologies, the team will create induced pluripotent stem cells from blood samples of women with endometriosis and develop a microfluidic device to study how these cells interact with immune cells. The goal is to uncover genetic differences and cellular behaviors that contribute to the condition, which could lead to better treatments and understanding of endometriosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are women and girls of reproductive age who have been diagnosed with endometriosis.
Not a fit: Patients who do not have endometriosis or are outside the reproductive age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for women suffering from endometriosis.
How similar studies have performed: Previous research has shown promise in using similar cellular and genetic approaches to understand complex conditions like endometriosis, indicating potential for success in this study.
Where this research is happening
CHICAGO, UNITED STATES
- NORTHWESTERN UNIVERSITY AT CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KIM, JI-YONG JULIE — NORTHWESTERN UNIVERSITY AT CHICAGO
- Study coordinator: KIM, JI-YONG JULIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.