Investigating the genetic causes of early-onset ischemic stroke
Whole Exome Sequencing Study of Early-Onset Ischemic Stroke
This study is looking at how genes might play a role in causing strokes in younger people, and if you join, you could help researchers find important genetic clues that could lead to better ways to prevent and treat these strokes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baltimore VA Medical Center NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10948104 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that contribute to early-onset ischemic stroke, particularly in younger individuals. By utilizing whole exome sequencing, the study aims to identify genetic variants that may increase susceptibility to stroke at a younger age. The research involves analyzing a large sample of carefully selected participants to uncover biological mechanisms that could lead to improved prevention and treatment strategies. Patients may be asked to provide genetic samples and health information to help researchers identify key genetic markers associated with early-onset stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 21 years old who have experienced an ischemic stroke or have a family history of early-onset stroke.
Not a fit: Patients who have not experienced a stroke or are over the age of 21 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and treatments for early-onset ischemic stroke, ultimately improving patient outcomes.
How similar studies have performed: Previous research has successfully identified genetic variants associated with other complex diseases using similar genetic association approaches.
Where this research is happening
Baltimore, United States
- Baltimore VA Medical Center — Baltimore, United States (Active)
Researchers
- Principal investigator: Cole, John W. — Baltimore VA Medical Center
- Study coordinator: Cole, John W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.