Investigating the endocannabinoid system's role in HIV-related neuropathic pain
Endocannabinoid system and HIV-related neuropathic pain
This study is looking at how the body's natural system for processing cannabis might help manage chronic nerve pain in people living with HIV, especially those who are on treatment, to see if it can make a difference in their pain relief.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Rio Grande Valley NIH-funded |
| Lab location | 1 site (Edinburg, United States) |
| Project ID | NIH-10852472 on NIH RePORTER |
What this research studies
This research explores how the endocannabinoid system may influence chronic neuropathic pain experienced by individuals living with HIV. It aims to determine whether this system is functional and effective in managing pain in HIV-positive patients, particularly in the context of current anti-retroviral therapies. The study employs a multidisciplinary approach, utilizing behavioral assessments, pharmacological interventions, and advanced biochemical techniques to gather comprehensive data on the interaction between cannabinoids and the endocannabinoid system in these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who experience chronic neuropathic pain.
Not a fit: Patients who do not have HIV or do not experience neuropathic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for individuals suffering from HIV-related neuropathic pain.
How similar studies have performed: While there is growing interest in the use of cannabis for pain management in HIV patients, this specific investigation into the endocannabinoid system's role in HIV-related neuropathic pain is novel and has not been extensively studied.
Where this research is happening
Edinburg, United States
- University of Texas Rio Grande Valley — Edinburg, United States (Active)
Researchers
- Principal investigator: Benamar, Khalid — University of Texas Rio Grande Valley
- Study coordinator: Benamar, Khalid
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.