Investigating the effects of Zika virus exposure during pregnancy on children's development

Childhood Outcome After In Utero ZIKV Exposure

NIH-funded research Children's Research Institute · NIH-10870183

This study is looking at how children who were exposed to the Zika virus before birth are developing as they grow up, especially at ages 5 and 7, to see how their brain and motor skills compare to other kids, so we can better support them as they start school.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChildren's Research Institute NIH-funded
Lab location1 site (Washington, United States)
Project IDNIH-10870183 on NIH RePORTER

What this research studies

This research focuses on children who were exposed to the Zika virus while in the womb, even if they do not show severe symptoms of congenital Zika syndrome. The study aims to assess their neurodevelopmental outcomes as they grow, particularly at ages 5 and 7. Researchers will compare these children to a control group to identify any differences in brain structure and function, as well as executive and motor skills. The goal is to develop guidelines for monitoring and supporting these children as they reach school age.

Who could benefit from this research

Good fit: Ideal candidates for this research are children who were exposed to the Zika virus in utero but do not have congenital Zika syndrome.

Not a fit: Patients who were not exposed to the Zika virus in utero or who exhibit severe congenital Zika syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and support for children affected by in utero Zika virus exposure, improving their developmental outcomes.

How similar studies have performed: Previous research has indicated that children exposed to Zika virus in utero may experience neurodevelopmental challenges, suggesting that this investigation is building on established findings.

Where this research is happening

Washington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.