NIH-funded research R01 grant

Investigating the effects of youth tackle football on brain development

Official title: Understanding the neurodevelopmental effects of youth tackle football participation

Funded at Ohio State University · NIH-11099820 · Data updated 2026-11-12

This study is looking at how playing youth tackle football might affect kids' brain development and thinking skills, and it's for young athletes and their families who want to understand the risks of brain injuries while playing.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 1, 2023
Project endMay 31, 2028
Funding year2025
Award (this year)$624,362
NIH project number5R01HD110401-03
Project IDNIH-11099820 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 8 to 12 years who are beginning their first season of tackle football.

Less likely to help

Patients who are not participating in youth tackle football or are older than 12 years may not receive direct benefits from this research.

What this research studies

This research examines how participation in youth tackle football may impact brain development and cognitive function. By tracking young athletes from the start of their first season, the study aims to identify risk factors associated with brain injuries and neurotrauma. Researchers will use advanced tools, such as instrumented mouthguards and strength testing, to gather data on the players' exposure to potential injuries and their neuromuscular control. The goal is to fill knowledge gaps regarding the long-term effects of tackle football on children's health.

Why it matters

Potential benefit: If successful, this research could lead to improved safety measures and guidelines for youth tackle football, ultimately protecting children's brain health.

How similar studies have gone: Previous research has highlighted concerns regarding brain injuries in contact sports, but this study aims to provide novel insights by establishing a true baseline for young athletes.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Caccese, Jaclyn B. — Ohio State University
  • Study coordinator: Caccese, Jaclyn B.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.