Investigating the effects of vaping on lung health in adolescents
Official title: Project 3 - Lung Health and Inflammation
Funded at Wake Forest University Health Sciences · NIH-11077349 · Data updated 2026-11-12
This study is looking at how vaping affects the lungs of teenagers who vape a lot, comparing it to the effects of smoking regular cigarettes, to help us understand the possible long-term health risks of vaping.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $267,237 |
| NIH project number | 5P01CA269048-03 |
| Project ID | NIH-11077349 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who are frequent vapers.
✕Less likely to help
Patients who do not vape or have never smoked may not receive direct benefits from this research.
What this research studies
This research focuses on understanding how vaping impacts respiratory health in adolescents, particularly those who vape frequently. The study aims to identify early physiological and molecular changes in the lungs associated with vaping, comparing these effects to those seen with traditional cigarette smoking. By examining oxidative stress and inflammation in the airways, the research seeks to provide critical insights into the potential long-term health consequences of vaping. The findings will help inform public health strategies and communication regarding vaping risks.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of respiratory diseases linked to vaping in adolescents.
How similar studies have gone: While research on vaping is emerging, this specific investigation into its early effects on lung health in adolescents is relatively novel and untested.
Where this research is happening
-
Wake Forest University Health Sciences
Winston-Salem, United States Active
Researchers
- Principal investigator: Hawkins, Gregory a — Wake Forest University Health Sciences
- Study coordinator: Hawkins, Gregory a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.