Investigating the effects of using opioids and alcohol together on brain function

Patterns and neurocognitive consequences of opioid-alcohol polysubstance use

NIH-funded research University of Florida · NIH-11288919

This study is looking at how using opioids and alcohol together affects thinking and behavior, so if you’ve ever wondered how these substances might impact your mind when used together, this research is for you!

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11288919 on NIH RePORTER

What this research studies

This research explores how the combined use of opioids and alcohol affects cognitive functions and behaviors. By studying patterns of substance use in individuals, the researchers aim to identify how these substances interact and whether their combined effects lead to greater cognitive impairments than when used separately. The study will involve assessing participants' substance use patterns and cognitive abilities over time, using advanced assessment tools. The findings will help to understand the underlying mechanisms of substance use disorders and their consequences.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who use both opioids and alcohol and are experiencing cognitive impairments.

Not a fit: Patients who do not use opioids or alcohol or those with other unrelated substance use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for individuals struggling with opioid and alcohol use disorders.

How similar studies have performed: Previous research has shown that polysubstance use can lead to significant cognitive impairments, indicating that this study's approach is relevant and necessary.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.