NIH-funded research R01 grant

Investigating the effects of toxic metals on brain health in children in rural Bangladesh

Official title: Building Capacity to study mixed metal-induced neurotoxicity in rural Bangladeshi children-A1

Funded at Sam Houston State University · NIH-10886149 · Data updated 2026-11-12

This study is looking at how harmful metals in the environment, like arsenic and lead, can affect the brain health and behavior of children in rural Bangladesh, while also helping local scientists learn more about this important issue.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSam Houston State University
NIH-funded
Lab location1 site (Huntsville, United States)
Project startSeptember 14, 2021
Project endJune 30, 2026
Funding year2024
Award (this year)$528,209
NIH project number5R01ES032149-04
Project IDNIH-10886149 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-20 years living in rural Bangladesh who may have been exposed to toxic metals.

Less likely to help

Patients who do not live in rural Bangladesh or who have not been exposed to the specified toxic metals may not benefit from this research.

What this research studies

This research focuses on understanding how exposure to toxic metals like arsenic, lead, manganese, and cadmium affects the brain health of children in rural Bangladesh. The study aims to build local research capacity by training Bangladeshi scientists to assess the neurobehavioral impacts of these metals on children's development. By collaborating with U.S. researchers, the project seeks to gather data that can inform public health strategies and interventions. The research will involve evaluating children's brain function and behavior in relation to their exposure to these environmental pollutants.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention of neurological disorders in children exposed to toxic metals.

How similar studies have gone: Previous studies have indicated neurobehavioral effects from single metal exposure, but this research aims to explore the combined effects of multiple metals, making it a novel approach.

Where this research is happening

  • Sam Houston State University
    Huntsville, United States
    Active

Researchers

  • Principal investigator: Khan, Khalid M. — Sam Houston State University
  • Study coordinator: Khan, Khalid M.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.