NIH-funded research NIH-funded research

Investigating the effects of tobacco product regulations in Appalachia

Official title: AppalTRuST Project 3: Impact of proposed tobacco product rules in Appalachia on consumption and product switching with the Experimental Tobacco Marketplace

Funded at University of Kentucky · NIH-10934529 · Data updated 2026-11-12

This study is looking at how new rules about tobacco products might change how people in rural Kentucky use them, especially focusing on things like nicotine levels and flavors, to help improve health in these communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Kentucky
NIH-funded
Lab location1 site (Lexington, United States)
Project startSeptember 30, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$620,150
NIH project number5U54DA058256-02
Project IDNIH-10934529 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include tobacco users residing in rural Appalachian areas, particularly those in Kentucky.

Less likely to help

Patients who do not use tobacco products or reside outside the Appalachian region may not benefit from this research.

What this research studies

This research aims to understand how proposed regulations on tobacco products will affect their use in rural Appalachian communities, particularly in Kentucky. By employing behavioral economic methods, the project will analyze consumption patterns and product switching among tobacco users in this underserved region. The study will focus on the impact of regulations such as limiting nicotine content and banning certain flavors, which could significantly alter the tobacco marketplace. Participants will be involved in assessing these changes and their implications for public health.

Why it matters

Potential benefit: If successful, this research could lead to improved public health outcomes by informing effective tobacco regulations that reduce consumption in Appalachian communities.

How similar studies have gone: Previous research has shown success in using behavioral economic methods to analyze tobacco consumption patterns, indicating that this approach is both relevant and potentially impactful.

Where this research is happening

  • University of Kentucky
    Lexington, United States
    Active

Researchers

  • Principal investigator: Koffarnus, Mikhail Nikolaas — University of Kentucky
  • Study coordinator: Koffarnus, Mikhail Nikolaas

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.