Investigating the effects of the apelin receptor on long-term health after preeclampsia
Official title: Apelin receptor axis and long-term consequences of preeclampsia
Funded at Wake Forest University Health Sciences · NIH-10790945 · Data updated 2026-11-12
This study is looking at how preeclampsia might affect women's heart and brain health later on, and it’s exploring a special system in the body that could help protect against these issues, with the hope of finding new ways to support women who have had preeclampsia.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | August 13, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $232,500 |
| NIH project number | 1R21HD114073-01 |
| Project ID | NIH-10790945 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who have experienced preeclampsia during pregnancy.
✕Less likely to help
Patients who have not had preeclampsia or those with unrelated health conditions may not benefit from this research.
What this research studies
This research focuses on understanding how preeclampsia, a pregnancy-related condition, can lead to long-term cardiovascular and cognitive issues in women. It explores the role of the apelin receptor system, which may help protect the brain and reduce inflammation after preeclampsia. By studying this connection, the research aims to identify potential therapeutic approaches that could improve the health outcomes of women who have experienced preeclampsia. The research will utilize established models to assess the neuroprotective effects of the apelinergic system.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve the long-term health and quality of life for women who have had preeclampsia.
How similar studies have gone: Previous research has shown promising results in exploring the neuroprotective effects of the apelinergic system, indicating potential for success in this area.
Where this research is happening
-
Wake Forest University Health Sciences
Winston-Salem, United States Active
Researchers
- Principal investigator: Yamaleyeva, Liliya M — Wake Forest University Health Sciences
- Study coordinator: Yamaleyeva, Liliya M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.