Investigating the effects of stroke and high blood pressure on brain function in Veterans
BLR&D Research Career Scientist Award Application
This study is looking at how stroke and high blood pressure impact brain health in Veterans, especially to find better ways to help them recover and prevent dementia after a stroke.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ralph H Johnson VA Medical Center NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-10946715 on NIH RePORTER |
What this research studies
This research focuses on understanding how stroke and high blood pressure affect brain function, particularly in Veterans who are at high risk for these conditions. It aims to explore the relationship between blood vessel health and cognitive impairment following a stroke. The study will utilize animal models to investigate the underlying mechanisms of stroke-related brain dysfunction and the potential differences in treatment responses based on gender and existing health conditions like diabetes. By examining these factors, the research seeks to identify new therapeutic targets for improving recovery and preventing dementia after stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are Veterans who have experienced a stroke or have high blood pressure and are at risk for cognitive impairment.
Not a fit: Patients who have not experienced a stroke or do not have high blood pressure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve recovery from stroke and reduce the risk of dementia in patients.
How similar studies have performed: While there have been numerous studies on stroke, this research takes a novel approach by focusing on the role of blood vessels and specific patient populations, which has not been extensively explored.
Where this research is happening
Charleston, United States
- Ralph H Johnson VA Medical Center — Charleston, United States (Active)
Researchers
- Principal investigator: Ergul, Adviye — Ralph H Johnson VA Medical Center
- Study coordinator: Ergul, Adviye
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.