Investigating the effects of statins on preventing dementia in older adults
PREVENTABLE Data Coordinating Center
This study is looking at whether taking moderate-intensity statins can help prevent dementia, like Alzheimer's, in older adults aged 75 and up who don’t have heart disease, and it aims to see if these medications can help them stay healthier for longer despite other health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10913408 on NIH RePORTER |
What this research studies
This research focuses on the role of moderate-intensity statins in preventing dementia, including Alzheimer's disease, in older adults aged 75 and above who do not have clinically evident coronary heart disease. The study aims to evaluate how these medications can prolong disability-free survival in patients with various health challenges, such as frailty and mild cognitive impairment. The Data Coordinating Center will oversee all data management and ensure the trial's success through careful monitoring and support for clinical sites. Patients will be actively followed up to assess the effectiveness and safety of the intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 75 and above who are at risk for dementia but do not have evident coronary heart disease.
Not a fit: Patients under 75 years old or those with clinically evident coronary heart disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new preventive strategies for dementia, improving the quality of life for older adults.
How similar studies have performed: Previous research has shown promising results in using statins for cardiovascular health, but this specific approach to dementia prevention is relatively novel.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Hammill, Bradley G — Duke University
- Study coordinator: Hammill, Bradley G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.