Investigating the effects of statins in patients with brain hemorrhages
StAtins Use in intRacereberal hemorrhage patieNts MRI (SATURN MRI) Ancillary Study
This study is looking at how staying on or stopping statin medications affects people who have had a brain bleed, especially those at higher risk of having another one, and it will involve brain scans to see how their brain health changes over two years.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10179775 on NIH RePORTER |
What this research studies
This research explores whether continuing or stopping statin medications affects patients who have experienced intracerebral hemorrhage (ICH), particularly those at high risk for recurrence. Participants will undergo brain MRI scans at the beginning and after 24 months to evaluate changes in brain health and the presence of small vessel disease markers. The study aims to provide clarity on the risks and benefits of statin therapy in this patient population, potentially influencing treatment decisions and improving patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates are patients who have experienced lobar intracerebral hemorrhage and are currently taking statins.
Not a fit: Patients who have not experienced intracerebral hemorrhage or those not on statin therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment guidelines for patients with brain hemorrhages, potentially reducing the risk of recurrence and improving quality of life.
How similar studies have performed: While there is limited prospective data on this specific topic, similar studies have shown the importance of statin therapy in cardiovascular health, indicating potential for impactful findings.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Selim, Magdy H — Beth Israel Deaconess Medical Center
- Study coordinator: Selim, Magdy H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.