Investigating the effects of rapid volume resuscitation in newborns with cardiac arrest due to blood loss.
Neonatal Hypovolemic Cardiac Arrest: Role of Early Rapid Volume Resuscitation
This study is looking at whether quickly giving extra blood to newborns who have heart problems from losing blood during birth can help them recover better than the usual slower method, and it's designed to improve care for babies in critical condition.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-10739265 on NIH RePORTER |
What this research studies
This research focuses on understanding how quickly replacing lost blood volume can help newborns who experience cardiac arrest due to asphyxia from fetal blood loss. The study aims to compare the effects of early rapid volume resuscitation versus the standard slower approach currently used in neonatal care. By using an ovine model, researchers will simulate conditions similar to those in newborns to gather data on how these interventions affect heart function and recovery. The goal is to improve outcomes for infants who are critically ill at birth.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns who have experienced birth asphyxia and are at risk of cardiac arrest due to significant blood loss.
Not a fit: Patients who are not newborns or those who do not experience birth asphyxia or related cardiac issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and recovery outcomes for newborns experiencing cardiac arrest due to blood loss.
How similar studies have performed: While the specific approach of rapid volume resuscitation in newborns is not widely tested, similar strategies in other populations have shown promise in improving outcomes.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Sankaran, Deepika — University of California at Davis
- Study coordinator: Sankaran, Deepika
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.