NIH-funded research R01 grant

Investigating the effects of prenatal COVID-19 exposure and vaccination on child development

Official title: The longer-term impact of prenatal exposure to SARS-CoV-2 infection and the COVID-19 vaccine on behavior, cognition, and brain functioning in the child

Funded at Icahn School of Medicine at Mount Sinai · NIH-10857242 · Data updated 2026-11-12

This study is looking at how being exposed to COVID-19 during pregnancy, either through infection or vaccination, might affect how children think, behave, and develop as they grow up, so we can better understand any long-term effects on their development.

More COVID-19 research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 19, 2022
Project endJune 30, 2027
Funding year2024
Award (this year)$716,474
NIH project number5R01HD109613-03
Project IDNIH-10857242 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation include pregnant individuals who have been exposed to SARS-CoV-2 or received the COVID-19 vaccine during pregnancy.

Less likely to help

Patients who are not pregnant or those whose pregnancies occurred before the COVID-19 pandemic may not benefit from this research.

What this research studies

This research examines how prenatal exposure to SARS-CoV-2 infection and COVID-19 vaccination affects children's behavior, cognition, and brain functioning. It aims to create a well-characterized birth cohort to assess the long-term impacts of these exposures on child development. By analyzing data from pregnant individuals and their children, the study seeks to understand potential risks associated with prenatal COVID-19 experiences. The research will involve monitoring children's development over time to identify any neurodevelopmental deviations.

Why it matters

Potential benefit: If successful, this research could provide critical insights into the long-term effects of prenatal COVID-19 exposure and vaccination, guiding future healthcare decisions for pregnant individuals and their children.

How similar studies have gone: Previous research has shown associations between maternal viral infections and neurodevelopmental issues in offspring, suggesting that this study's approach is grounded in established findings.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Rommel, Anna-Sophie — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Rommel, Anna-Sophie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.