Investigating the effects of prenatal alcohol exposure on fetal development
Project 2: Prenatal Alcohol Exposure (PAE) and Fetal Alcohol Spectrum Disorder (FASD)
['FUNDING_OTHER'] · NORTH CAROLINA CENTRAL UNIVERSITY · NIH-10897324
This study is looking at how drinking alcohol during pregnancy can cause developmental issues in babies, like Fetal Alcohol Spectrum Disorders (FASD), and it aims to find ways to prevent or treat these problems using special models like zebrafish and mice.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTH CAROLINA CENTRAL UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-10897324 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how prenatal alcohol exposure can lead to developmental disorders, specifically Fetal Alcohol Spectrum Disorders (FASD). By using advanced models such as genetically modified zebrafish and mice, the study aims to identify the molecular pathways affected by alcohol exposure that lead to limb and facial defects. The researchers will employ techniques like gene knockout and high-throughput screening of chemical compounds to find potential treatments or preventive measures. This work seeks to provide insights that could ultimately improve clinical practices and reduce the incidence of FASD.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals who consume alcohol and may be at risk of having children with FASD.
Not a fit: Patients who have not been exposed to alcohol during pregnancy or those without any developmental concerns related to FASD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or mitigating the effects of Fetal Alcohol Spectrum Disorders in affected individuals.
How similar studies have performed: Previous research has shown promising results in understanding the mechanisms of alcohol-induced developmental defects, suggesting that this approach could yield valuable insights.
Where this research is happening
DURHAM, UNITED STATES
- NORTH CAROLINA CENTRAL UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILLIAMS, KEVIN PETER — NORTH CAROLINA CENTRAL UNIVERSITY
- Study coordinator: WILLIAMS, KEVIN PETER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.