Investigating the effects of potassium citrate on bone strength in chronic kidney disease patients
Bone In CKD Alkali Response Pilot Trial (BICARb Pilot Trial)
This study is looking at whether taking potassium citrate can help strengthen bones in people with chronic kidney disease, including both kids and adults, by comparing it to a placebo over six months.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-10896323 on NIH RePORTER |
What this research studies
This research focuses on understanding how potassium citrate supplementation can improve bone strength in patients with chronic kidney disease (CKD). The study will involve a 6-month randomized clinical trial with both children and adults, comparing the effects of potassium citrate to a placebo. Researchers will measure bone strength using advanced imaging techniques and assess urinary acid levels to gain insights into how potassium citrate influences bone health. The goal is to find safe and effective treatments to reduce fracture risks associated with CKD.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adults with stages 2 and 3 chronic kidney disease.
Not a fit: Patients with advanced chronic kidney disease (stage 4 and 5) may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that improve bone health and reduce fracture rates in patients with chronic kidney disease.
How similar studies have performed: Previous research has shown promising results with potassium citrate in improving bone health, making this approach a potentially valuable addition to CKD management.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Reidy, Kimberly Jean — Albert Einstein College of Medicine
- Study coordinator: Reidy, Kimberly Jean
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.